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NFL Betting Previews | Spooky Express
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Arizona Cardinals vs. Buffalo Bills

September 8, 2024


Football season is back, and what better way to kick things off than with a thrilling matchup between the Arizona Cardinals and the Buffalo Bills? Whether you're an NFL fanatic, a seasoned sports bettor, or someone looking for an exciting Sunday, this game promises to deliver.


With high stakes, powerful plays, and strategic maneuvers, we're breaking down everything you need to know to make intelligent betting choices.


Game Preview

This Sunday, September 8, the Arizona Cardinals will face off against the Buffalo Bills at Highmark Stadium. The anticipation for this game is electric, with both teams eager to start the season on a high note.


The odds are set at our friends at MyBookie as follows:


  • Moneyline (ML): Cardinals +225 (bet $100 to win $225) | Bills -275 (bet $275 to win $100)
  • Against the spread (ATS): Cardinals +6 (-110) | Bills -6 (-110)
  • Over/Under (O/U): 48 (O: -115 | U: -105)


Arizona Cardinals


The Cardinals are looking to bounce back from two consecutive 4-win seasons, and they're pinning their hopes on a rejuvenated Kyler Murray. Murray showed promise in the second half of last season, and with Ohio State standout Marvin Harrison Jr. joining the fold, there's cautious optimism in the air.


Kyler Murray has faced his share of criticism, with inconsistencies and injuries plaguing his career thus far. All eyes will be on him to see if he can turn things around and lead his team to victory. If Murray falters, the Cardinals may soon search for a new quarterback.


Arizona's defense has been a weak spot. It gave up 26.8 points per game last season, ranking 31st in the NFL. The preseason didn't show much improvement, as it allowed 75 points in three games. Facing one of the league's best quarterbacks, Josh Allen, won't make things any easier.


Buffalo Bills


The Bills are coming off another strong season, winning the AFC East and making it to the playoffs, only to lose to the Kansas City Chiefs. With an 11-6 regular-season record, they've proven they're a force to be reckoned with. With 44 combined touchdowns last season, Josh Allen remains a pivotal figure in their quest for Super Bowl glory.


One significant setback for the Bills is the injury to their defensive leader, Matt Milano. Milano's absence has been felt since Week 5 of last season, and his bicep injury during training camp means he won't be back anytime soon. The defense needs to step up in his absence.


The Bills must also find a way to get their receivers involved without Stefon Diggs and Gabe Davis. While Diggs didn't have a standout season, his presence was still a threat to defenses. Buffalo will need to innovate and adapt its offense to maintain its high-scoring ways.


Betting Predictions


Let's break down the critical betting options:


Bills Moneyline (-278)Betting on the Bills to win straight up is a solid choice. They have a superior team and home-field advantage. Josh Allen and the company will likely exploit Arizona's defense weaknesses, but this is the NFL, and anything is possible, especially during opening week, so playing the moneyline here is NOT recommended.


Bills -5.5 ATS (-105)The Bills can win by at least a touchdown. Arizona's roster has gaps, and facing a team of Buffalo's caliber will be a tough challenge. Playing the point spread here at MyBookie is much more appealing to us.


Over 48 (-112)This high point total reflects the potential offensive explosion from both teams. Buffalo's potent offense and Arizona's defensive struggles make the over an appealing option. Among all the wagers you can play, this one seems the most valuable, as we have two high-powered offenses that will both be working for you!


NFL PICK: OVER 48