The 2-0 Louisville Cardinals will travel to take on the 1-1 Indiana Hoosiers in week 3 of the college football season on Saturday afternoon. 

Louisville enters this game with a record of 2-0 following wins on the road against the Georgia Tech Yellow Jackets by a score of 39-34 and at home against the Murray State Racers by a score of 56-0 while the Indiana Hoosiers enter this game with a record of 1-1 following a loss at home against the Ohio State Buckeyes by a score of 3-23 and a win at home against the Indiana State Sycamores by a score of 41-7. 

Which team will come away with the win in this matchup on Saturday afternoon? Let’s take a deeper dive into how these teams are performing this season.

The Louisville Cardinals enter this game with a record of 2-0 following a 56-0 win at home against the Murray State Racers while covering the 43.5-point spread as a home favorite in week 1 of the college football season. Louisville scored 56 points while compiling 690 total yards offensively which included 346 passing yards and 344 rushing yards while shutting out the Racers and allowing a total of 166 total yards defensively which included 72 passing yards and 94 rushing yards. 

Jack Plummer led the team in passing, completing 16 of 22 attempts for 247 yards with a touchdown and two interceptions. Jawhar Jordan led the team in rushing with seven carries for 135 yards and two touchdowns while adding two receptions for 43 yards. Jamari Thrash led the team in receiving with three receptions for 82 yards and a touchdown.

Indiana enters this game with a record of 1-1 following a 41-7 win at home against the Indiana State Sycamores while covering the 31-point spread as a home favorite. The Hoosiers scored 41 points while compiling 558 total yards offensively which included 344 passing yards and 214 rushing yards while allowing 7 points and 93 total yards defensively which included 21 passing yards and 72 rushing yards. 

Tayven Jackson led the team in passing, completing 18 of 21 attempts for 236 yards while adding nine rushing yards and a touchdown. Jaylin Lucas led the team in rushing with 10 carries for 88 yards and two touchdowns while adding four receptions for 39 yards. Omar Cooper Jr. led the team in receiving with seven receptions for 101 yards.

BookMaker has the Louisville Cardinals listed as 10-point favorites on the road against the Indiana Hoosiers in week 3 of the college football season on Saturday afternoon. This will be the first time in the history of these programs that they will face each other in college football. Louisville is 1-1 ATS overall and 1-1 ATS as a favorite this season while the Indiana Hoosiers are 2-0 ATS overall, 2-0 ATS at home, and 1-0 ATS as an underdog.

Louisville is the more talented team this season, however, Indiana is undefeated against the spread this season going 2-0 ATS overall and 2-0 ATS at home. I look for Louisville to get the win, however, I look for the game to be closer than Vegas projects which is why I am taking the Indiana Hoosiers +10 at home against the Louisville Cardinals on BookMaker on Saturday afternoon in week 3 of the college football season.