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NFL Betting Preview: Arizona Cardinals vs. San Francisco 49ers

December 17, 2023



Two NFC West rivals will square off on Sunday afternoon in week 15 of the NFL season when the San Francisco 49ers travel to Glendale, Arizona to face the Arizona Cardinals at State Farm Stadium with the game scheduled to start at 4:05 PM ET and will air on CBS.

 

With Green Bay’s loss on Monday night, the San Francisco 49ers became the first team in the NFL to clinch a spot in the playoffs as they enter this game with a record of 10-3 and have won their last five games including a 28-16 win at home against the Seattle Seahawks. The 49ers have been one of the most complete teams in the league and are looking like the team to beat in the NFC as they are averaging the 3rd most points per game in the league with an average of 29.23 points per game while allowing the fewest points per game with an average of 15.77 points per game. Brock Purdy is having an MVP-level season as he enters this game having completed 252 of 359 attempts for 3,553 yards with 25 touchdowns and seven interceptions while rushing for 138 yards and two touchdowns.

 

The 49ers rank 3rd in the NFL in passing yards with an average of 262.69 passing yards per game. The San Francisco 49ers will look to extend their winning streak to six games when they travel to face the Arizona Cardinals.

 

The Arizona Cardinals have been one of the worst teams in the NFL this season as they enter this game with the 2nd worst record in the NFC and are tied with the New England Patriots for the 2nd worst record in the NFL with a record of 3-10, however, they are coming off a 24-10 win on the road against the Pittsburgh Steelers before their bye week which also ended their two-game losing streak.

 

The Cardinals are averaging the 7th fewest points per game in the NFL with an average of 17.69 points per game and have the 3rd worst passing offense as they are averaging 172.38 passing yards per game. Kyler Murray has looked average at best this season as he enters this game having completed 79 of 130 attempts for 864 yards with three touchdowns and two interceptions while rushing for 106 yards and three touchdowns. The defense for the Cardinals has also been the 3rd worst scoring defense in the league as they are allowing an average of 25.46 points per game.

 

The Arizona Cardinals will look to build momentum following the win against the Pittsburgh Steelers and try to win back-to-back games for the first time this season when they host the San Francisco 49ers on Sunday afternoon.

 

BookMaker has the San Francisco 49ers listed as 12.5-point favorites on the road against the Arizona Cardinals on Sunday afternoon in week 15 of the NFL season. San Francisco has won six of the last ten including the previous three meetings. The Cardinals are 5-4-1 ATS in the last ten while the 49ers have covered the spread in the last three games in the series. The San Francisco 49ers are 7-6 ATS overall, 4-3 ATS on the road, 7-6 ATS as a favorite, and 2-2 ATS in division games this season while the Arizona Cardinals are 7-6 ATS overall, 4-2 ATS at home, 7-6 ATS as an underdog, and 0-4 ATS in division games on the year.

San Francisco is one of the best teams in the NFC while Arizona is one of the worst as the 49ers enter this game with a record of 10-3 while the Cardinals are 3-10.

 

The San Francisco 49ers have also been the better team in the series, winning six of the last ten including three straight against the Cardinals while also covering the spread in three straight games in the series. The Cardinals have yet to cover the spread in any division game this season as they are 0-4 ATS in division games this season. Buy the .5 point and lay the points with the San Francisco 49ers when they travel to face the Arizona Cardinals.

 

Spooky Express Pick: San Francisco 49ers -12