The Arizona Cardinals were huge underdogs heading into their week 3 matchup against the Dallas Cowboys as they were 11-point underdogs, however, they managed to get their first win of the season. San Francisco is looking like the best team in the NFC this season as they are one of only three teams that are undefeated heading into week 4 of the NFL season. Will the 49ers win in a rout at home or will the Cardinals keep the game closer than expected in a battle of NFC West teams? Let’s take a look at how these teams have fared this season.

The Arizona Cardinals enter this game with a record of 1-2 following a 28-16 win at home against the Dallas Cowboys while covering the 11-point spread as a home underdog in week 3 of the NFL season. Arizona scored 28 points while compiling a total of 400 yards offensively which included 189 passing yards and 222 rushing yards while allowing 16 points and 416 total yards defensively which included 249 passing yards and 185 rushing yards. Joshua Dobbs led the team in passing, completing 17 of 21 attempts for 189 yards and a touchdown while adding 55 rushing yards. James Conner led the team in rushing with 14 carries for 98 yards and a touchdown while adding two receptions and 18 yards. Michael Wilson led the team in receiving, catching both targets for 86 yards.

San Francisco enters this game with a record 3-0 following a 30-12 win at home against the New York Giants while covering the 10.5-point spread as a home favorite in week 3 of the NFL season. The 49ers scored 30 points while compiling a total of 441 yards offensively which included 310 passing yards and 141 rushing yards while allowing 12 points and 150 total yards defensively which included 137 passing yards and 29 rushing yards. Brock Purdy led the team in passing, completing 25 of 37 attempts for 310 yards and two touchdowns. Christian McCaffrey led the team in rushing with 18 carries for 85 yards and a touchdown while adding five receptions for 34 yards. Deebo Samuel led the team in receiving, catching six of 12 targets for 129 yards and a touchdown.

BookMaker has the San Francisco 49ers listed as 14-point favorites at home against the Arizona Cardinals on Sunday afternoon in week 4 of the NFL season. The teams have split the last ten games in the series while San Francisco has won two of the last three contests while going 2-1 ATS in those matchups. Arizona is 3-0 ATS overall, 1-0 ATS on the road, and 3-0 ATS as an underdog this season while the San Francisco 49ers are 2-1 ATS overall, 1-0 ATS at home, 2-1 ATS as a favorite, and 0-1 ATS in division games on the year.

San Francisco is arguably the best team in the NFL this season and has been the better team most recently in the series, winning two of the last three games. However, Arizona has been the better team at covering the spread in the last ten games in the series, going 6-3-1, and has covered all three games this season going 3-0 ATS overall. As a result, I am taking the Arizona Cardinals +14 on the road against the San Francisco 49ers in week 4 of the NFL season on BookMaker.