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NFL Betting Preview: Cleveland Browns vs. San Francisco 49ers

October 15, 2023


The San Francisco 49ers will travel to Cleveland, Ohio to face the Cleveland Browns at Cleveland Browns Stadium on Sunday afternoon at 1:00 PM ET with the game airing on Fox in week 6 of the NFL season.

San Francisco enters this game with a record of 5-0 following a 42-10 win at home against the Dallas Cowboys while covering the 3.5-point spread as a home favorite in week 5 of the NFL season. The 49ers scored 42 points while compiling a total of 421 yards offensively which included 253 passing yards and 170 rushing yards while allowing 10 points and 197 total yards defensively which included 161 passing yards and 57 rushing yards. Brock Purdy led the team in passing, completing 17 of 24 attempts for 252 yards and four touchdowns. Jordan Mason led the team in rushing with ten carries for 69 yards and a touchdown. George Kittle led the team in receiving, catching three of four targets for 67 yards and three touchdowns.

The Cleveland Browns enter this game with a record of 2-2 following a 3-28 loss at home against the Baltimore Ravens while failing to cover the 1.5-point spread as a home underdog in week 4 of the NFL season. Cleveland scored 3 points while compiling a total of 166 yards offensively which included 121 passing yards and 93 rushing yards while allowing 28 points and 296 total yards defensively which included 186 passing yards and 131 rushing yards. Dorian Thompson-Robinson led the team in passing, completing 19 of 36 attempts for 121 yards and three interceptions while adding 24 rushing yards. Pierre Strong Jr. led the team in rushing with five carries for 49 yards. David Njoku led the team in receiving, catching six of seven targets for 46 yards.

BookMaker has the San Francisco 49ers listed as 9.5-point favorites on the road against the Cleveland Browns on Sunday afternoon in week 6 of the NFL season. Cleveland has won three of the last five while San Francisco has won two of the last three games in the series. The Browns are 3-2 ATS in the last ten while the 49ers are 2-1 ATS in the last three meetings. San Francisco is 4-1 ATS overall, 1-1 ATS on the road, and 4-1 ATS as a favorite this season while the Cleveland Browns are 2-2 ATS overall, 2-1 ATS at home, and 0-1 ATS as an underdog on the year.

Through the first five weeks of the season, the San Francisco 49ers are looking like the most complete and most dominant team in the NFL as they enter this game with a record of 5-0 and have won by double-digits in four of their five games on the year. The 49ers are 4-1 ATS overall this season and have been the better team most recently at covering the spread in the series going 2-1 ATS in the previous three meetings. I look for those trends to continue when the 49ers travel to take on the Browns in week 6 of the NFL season which is why I am buying the .5 point and taking the San Francisco 49ers -9.

Spooky Express Pick: San Francisco 49ers -9