The Denver Broncos are 0-1 in the preseason following a 17-18 loss on the road against the Arizona Cardinals on Friday in week 1 of the NFL preseason.

Meanwhile, the San Francisco 49ers are 0-1 in the preseason following a 7-34 loss on the road against the Las Vegas Raiders in week 1 of the NFL preseason on Sunday.

BookMaker has the Denver Broncos listed as 4-point favorites on the road against the San Francisco 49ers and has set the total for the over/under plays at 38.5 points. Which team will get their first win of the preseason with a win in this matchup on Saturday night? Let’s take a closer look at how these teams have played this year.

Denver Broncos Team Preview

The Denver Broncos enter this game with a record of 0-1 in the NFL preseason following a 17-18 loss on the road against the Arizona Cardinals in week 1 of the preseason. The Broncos are 0-1 ATS overall, 0-1 ATS on the road, and 0-1 ATS as a favorite this season.

Offensively, Denver is averaging 17 points per game in the preseason. The Broncos are averaging 312 total yards, 200 passing yards, and 122 rushing yards per game in the NFL preseason. Russell Wilson leads the team in passing completing 7 of 13 attempts for 93 yards and a touchdown. Samaje Perine leads the team in rushing with six carries for 26 yards. Jerry Jeudy leads the team in receiving with two receptions for 40 yards and a touchdown.

Defensively, the Broncos are allowing an average of 18 points per game in the NFL preseason. Denver is allowing an average of 309 total yards, 238 passing yards, and 101 rushing yards per game in the preseason.

San Francisco 49ers Team Preview

The San Francisco 49ers enter this game with an overall record of 0-1 in the preseason following a 7-34 loss against the Las Vegas Raiders in week 1 of the NFL preseason. The 49ers are 0-1 ATS overall this season.

Offensively, the 49ers are averaging 7 points per game in the NFL preseason. San Francisco is averaging 283 total yards, 232 passing yards, and 69 rushing yards per game in the preseason. Trey Lance leads the team in passing completing 10 of 15 attempts for 112 yards and a touchdown. Tyrion Davis-Price leads the team in rushing with nine carries for 29 yards. Ronnie Bell leads the team in receiving with three receptions for 58 yards.

Defensively, San Francisco is allowing an average of 34 points per game in the preseason. The 49ers are allowing an average of 266 total yards, 152 passing yards, and 120 rushing yards in the NFL preseason.

Series Trends and Game Pick

Both teams are 4-4 in the last eight games in the series, however, Denver has outscored San Francisco by an average of 23.12 to 19.25 points per game while both teams are 4-4 ATS in those matchups. The Broncos have won two of the last three games in the series and have won by an average score of 22.33 to 15.67 while going 2-1 ATS in those contests.

The under has hit in five of the last eight games in the series with the teams combining for an average of 42.37 points per game in those contests. The under has hit in two of the last three games in the series with the teams combining for an average of 38 points per game in those matchups.

Denver has been the better team most recently in the series, winning two of the last three games. The Broncos are 2-1 ATS in the last three games in the series. As a result, I am taking the Denver Broncos -4 on BookMaker for this matchup on Saturday night.